Table 3.

Coagulation parameters

	RM1				RM2				RM3				RM7	RM8	Reference range*
	Day 0	Day 1	Day 5	Day 7	Day 0	Day 1	Day 5	Day 10	Day 0	Day 5	Day 10	Day 14
Prothrombin, seconds	—	9.9	8.9	9.7	—	10.1	9.1	8.8	10.1	9.6	9.2	9.3	9.7	10.4	10.7 ± 4.5
Activated partial thromboplastin time, seconds	45.6	46.5	33.7	33.6	—	40.2	32.5	37.4	59.0	29.6	42.0	44.5	48.5	34.6	25 ± 20
D-dimer, ng/mL	—	< 150	486	1102	< 150	862	1170	1131	—	586	725	882	< 150	< 150	< 260
Antithrombin III, percentage	—	134	174	128	120	138	124	138	—	140	138	137	125	113	82-133
Soluble fibrin monomers, mg/dL	—	< 7	< 7	< 7	—	40	< 7	< 7	< 7	< 7	< 7	< 7	< 7	< 7	< 10
Thombin-antithrombin complexes, μg/mL	19.0	7.2	> 60	16.8	—	> 60	> 60	> 60	14.8	> 60	11.6	53.0	7.0	7.6	4-33
Protein C, percentage	301	< 10	292	276	151	221	> 301	> 301	299	269	> 301	290	140	134	76-208
Protein S, percentage	83	166	151	127	86	94	164	175	149	123	101	114	47	48	62-153

— indicates not applicable.

^*Reference ranges are based upon those reported by Matsuzawa et al.³¹