Table 2.
Comparison of accuracy of SNVMix1, SNVMix2 and SNVMix combined with base and mapping quality thresholding
Model | Run | Train AUC | TP | FP | TN | FN | Sens | Prec | F-measure |
---|---|---|---|---|---|---|---|---|---|
SNVMix1 | 10× | 0.9880 | 305 | 192 | 0 | 0 | 1.0000 | 0.6137 | 0.7606 |
40× | 0.9924 | 293 | 107 | 85 | 12 | 0.9607 | 0.7325 | 0.8312 | |
SNVMix2 | 10× | 0.9905 | 299 | 162 | 30 | 6 | 0.9803 | 0.6486 | 0.7807 |
40× | 0.9929 | 290 | 107 | 85 | 15 | 0.9508 | 0.7305 | 0.8262 | |
SNVMix2+thresholding | mQ50_bQ20 (10×) | 0.9882 | 287 | 88 | 104 | 18 | 0.9410 | 0.7653 | 0.8441 |
mQ50_bQ15 (40×) | 0.9928 | 287 | 71 | 121 | 18 | 0.9410 | 0.8017 | 0.8658 |