FIGURE 6.
Overall structure of haditoxin. A, stereo view of a portion of the final 2Fo − Fc map of haditoxin. The map was contoured at a level of 1.0 σ. B, monomers A and B are shown in blue and red, respectively. Disulfide bonds are shown in yellow. N and C termini (N-term and C-term), β-strands, and loops I, II, and III are labeled. C, structure-based alignment of three-finger toxins. Color coding of conserved residues is provided by boxed red text, and color coding of invariant residues is provided by red highlight. Accession numbers are shown on the left, and secondary structural elements of haditoxin are shown on top. Numbering is shown for haditoxin only. Sequence alignment was done by Strap (82) and displayed with ESPript (83).