TABLE 1.
Summary of ARC40 alleles
| Allele | Mutation | Growth phenotype | Possible interaction |
|---|---|---|---|
| ARC40 | Wild type | NEa | |
| arc40-101 | K7A,D8A,K9A | NE | |
| arc40-103 | D30A,K31A | NE | |
| arc40-104 | E39A,D41A | NE | |
| arc40-105 | K60A,D61A | NE | |
| arc40-106 | D63A,K64A | NE | |
| arc40-107 | D83A,R84A | NE | p19/ARPC4 |
| arc40-108 | E90A | NE | |
| arc40-109 | D94A,K98A | NE | |
| arc40-110 | R105A,R108A | NE | p19/ARPC4 |
| arc40-111 | E137A,E139A | NE | |
| arc40-112 | K146A,K149A | NE | |
| arc40-114 | K185A,D188A | NE | |
| arc40-115 | K190A,E191A | NE | |
| arc40-116 | R209A,E210A | NE | |
| arc40-118 | E227A,R228A | Slow growth at 37 °C | |
| arc40-119 | D266A,E268A | NE | |
| arc40-120 | E283A,E286A | NE | |
| arc40-121 | K289A,K292A | NE | |
| arc40-122 | D298A,K301A | NE | |
| arc40-123 | D312A,E313A | NE | |
| arc40-124 | D319A,E320A | NE | |
| arc40-125 | R330A,K331A | NE | |
| arc40-126 | K333A,E334A | NE | |
| arc40-127 | D336A,K338A | NE | |
| arc40-128 | K340A,D344A | NE | |
| arc40-129 | E347A,E351A | NE | |
| arc40-130 | E356A,R358A | NE | |
| arc40-131 | E362A | NE | |
| arc40-132 | D376A,K378A | NE | |
| arc40-133 | D295A,K296A | NE | |
| arc40-139 | D83A,R84A,R105A,R108A | Lethal | p19/ARPC4 |
| arc40-140 | A328E,F332A | Lethal | VCA domain |
| arc40-141 | R129A | Lethal | p15/ARPC5 |
| arc40-142 | D235A,E254A | NE | p15/ARPC5 |
| arc40-143 | K146A,K149A,K185A,D188A | Lethal | F-actin? |
| arc40-144 | D94A,K98A,R105A,R108A | NE | F-actin? |
| arc40-145 | R105A,R108A,K146A,K149A | NE | F-actin? |
| arc40Δ311–340 | Deletion of 311–340 | Lethal | VCA domain |
a NE, no effect.