Figure 2. Apocynin significantly reduces carbonyl content in the retinas of postnatal day (P) 25 rd1+/+ mice.
Starting at P11, rd1+/+ mice were given daily intraperitoneal injections of vehicle or vehicle containing apocynin. Mice were euthanized at P25 and protein carbonyl content was measured by ELISA of retinal homogenates as described in Methods. The mean (±SEM) carbonyl content per mg retinal protein was significantly greater in vehicle-treated rd1+/+ mice compared to those treated with apocynin (*p<0.001 by unpaired Student’s t-test).