Fig. 3.

Decrease in the Level of Parvalbumin (PV) Expression in the Prefrontal Cortex, Observed Both in (A) Schizophrenia Patients (mRNA Level) and (B) A Mouse Model for Schizophrenia (disrupted in schizophrenia-1 [DISC1] Transgenic Mice Expressing the Truncated, Dominant-Negative Form of “DISC1”). There was decrease in PV staining but not in calbindin (CB) staining. A, reprinted by permission from Nature Reviews Neuroscience³¹; 2005. B, adapted from Proceedings of the National Academy of Sciences United States of America.⁸¹