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Different types of zinc binding sites. Our cluster selection approach divides several clusters into smaller groups of zinc binding site environments. Many of these represent different types of zinc binding sites: (from left to right) coordination by four CYS residues, coordination by three CYS and one HIS residue, coordination by two CYS and two HIS residues (C2H2 type), and coordination of multiple zinc ions by many diverse residues, including CYS, HIS, ASP, GLU, and water.
