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. Author manuscript; available in PMC: 2010 Mar 5.
Published in final edited form as: Cancer Res. 2007 Jan 1;67(1):318–325. doi: 10.1158/0008-5472.CAN-06-2164

Figure 4.

Figure 4

[5,5′-3H2]AHPN binding to SHP in MDA-MB-468 cells. A, Scatchard plot of [5,5′-3H2]AHPN binding to SHP. Scatchard plots and analysis were done as described in Materials and Methods. Results are representative of four independent experiments. B, [5,5′-3H2]AHPN and [3H]tRA binding to SHP. [5,5′-3H2]AHPN and [3H]tRA were added to a concentration of 5 nmol/L. Nonlabeled ligand was added to a final concentration of 50 μmol/L.C, [5,5′-3H2]AHPN binding to GST-SHP. D, correlation between [5,5′-3H2]AHPN binding to SHP and apoptosis induction in MDA-MB-468 cells.