Table 1. Mouse embryo survival data.
Age (days) | Total No. | Ire1α +/+ | Ire1α +/− | Ire1α −/− | Resorbed |
E 8.5 | 35 | 4 (11%) | 21 (60%) | 8 (23%) | 2 |
E 9.5 | 34 | 8 (24%) | 19 (56%) | 4 (12%) | 3 |
E10.5 | 84 | 19 (23%) | 45 (54%) | 15 (18%) | 5 |
E11.5 | 34 | 8 (24%) | 17 (50%) | 6 (18%) | 3 |
E12.5 | 33 | 7 (21%) | 14 (42%) | 2 (6%)a | 10 |
E13.5 | 25 | 6 (24%) | 14 (56%) | 2 (8%) | 3 |
Ire1+/− heterozygous animals were crossed and embryos as well as placenta were collected at various stages of development starting at embryonic day 8.5.