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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Cancer Prev Res (Phila). 2010 Feb 23;3(3):371–380. doi: 10.1158/1940-6207.CAPR-09-0152

Table 1.

a. Treatment Protocol of Selenomethionine Experiment
Group Number of
Animals		 From Day 1 From Day 7 After 26 Weeks Terminal Sacrifice
1 30 Testosterone plus
17β-estradiol		 Control diet (NIH-07) Testosterone plus
estradiol replacement		 54 wks after start
2 30 Testosterone plus
17β-estradiol		 Selenomethionine mixed
in diet at 1.5 mg/kg (as
selenium)		 Testosterone plus
estradiol replacement		 54 wks after start
3 30 Testosterone plus
17β-estradiol		 Selenomethionine mixed
in diet at 3.0 mg/kg (as
selenium)		 Testosterone plus
estradiol replacement		 54 wks after start
b. Treatment Protocol of α-Tocopherol Experiment
Group Number of
Animals		 From Day 1 From Day 7 After 26 Weeks Terminal Sacrifice
1 30 Testosterone plus
17β-estradiol		 Control diet (NIH-07) Testosterone plus
estradiol replacement		 54 wks after start
2 30 Testosterone plus
17β-estradiol		 α-Tocopherol mixed in
diet at 2,000 mg/kg		 Testosterone plus
estradiol replacement		 54 wks after start
3 30 Testosterone plus
17β-estradiol		 α-Tocopherol mixed in
diet at 4,000 mg/kg		 Testosterone plus
estradiol replacement		 54 wks after start