Table 1.
Treatment* N=36 |
Symptomatic treatment* N=22 |
No treatment* N=12 |
p-value | |
---|---|---|---|---|
Mean person-months of follow-up (IQR) | 26 (18–36 ) | 29 (20–36) | 27 (17–36) | 0.74 |
Mean proportion of follow-up time with bacteriuria (IQR) |
0.29 (0.09–0.40) | 0.31 (0.16–0.40) | 0.66 (0.46–0.91) | <0.001 |
Mean duration of bacteriuria in months (IQR) | 2.2 (1.6–2.9) | 2.5 (1.8–3.1) | 3.7 (1.31–5.4) | 0.04 |
Mean length of carriage of a single strain in months (IQR) |
2.4 (1.6–2.8) | 2.8 (2.1–3.2) | 4 (1.6–6.6) | 0.03 |
Mean number of times received treatment (IQR) |
3.2 (1–4) | 2.0 (1–3) | -- | 0.05 |
Mean proportion of treatment courses followed by recurrent E. coli (IQR) |
0.76 (0.67–1) | 0.65 (0.5–1) | -- | 0.18 |
Mean proportion of recurrence caused by reinfection**(IQR) |
0.64 (0.25–1) | 0.43 (0–1) | -- | 0.16 |
“Treatment” indicates women originally randomized to treatment for asymptomatic bacteriuria (ASB). “Symptomatic treatment” indicates women originally randomized to no treatment for ASB, but who received antimicrobials for symptomatic urinary infections or other indications over the course of their follow-up. “No treatment” indicates women originally randomized to no treatment for ASB and who did not receive any antimicrobials for the duration of their follow-up.
Reinfection is defined as recurrent E. coli that is genetically different from the pre-treatment strain.
Abbreviations: N=number of women, IQR = inter-quartile range.