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. Author manuscript; available in PMC: 2010 Mar 7.
Published in final edited form as: J Infect Dis. 2008 Jun 15;197(12):1752–1761. doi: 10.1086/588196

Table 5.

Multiple regression analysis for inflammation in relation to cytokine levels in Helicobacter pylori–positive patients with nonulcer dyspepsia.

Antrum
Corpus
Histology Explanatory variable PRC ± SE P PRC ± SE P
MNC IL-18 protein level 0.0026 ± 0.0005 <.001 0.0011 ± 0.0007 .004
IL-18 mRNA level 0.54 ± 0.13 <.001 0.51 ± 0.08 <.001
PMN IL-18 protein level 0.0004 ± 0.0002 .092 0.0009 ± 0.0005 .006
IL-18 mRNA level 0.37 ± 0.16 .041 0.59 ± 0.18 .009
IFN-γ mRNA level 0.34 ± 0.19 .056

NOTE. Final models are presented. Adjusted for age, sex, and H. pylori density at the same topographical site. The partial regression coefficient (PRC) provides an estimate of the expected results of the mononuclear cell (MNC) scores. For example, in the antrum, MNC scores would be expected to increase 0.54 if interleukin (IL)–18 mRNA scores increase by 1. IFN, interferon; PMN, polymorphonuclear leukocyte.