Wild-type mice (WT) and CAR knockout mice (KO) were administered corn oil (oil), baicalein (Ba), chrysin (Ch) or TCPOBOP (TC) for 3 days, and the cyp2b10 mRNA content of their livers was quantified by real-time PCR analysis. A significant increase in cyp2b10 mRNA content versus the oil-treated control (Welch's t-test, P < 0.05, n=4) was detected only in wild-type mice fed chrysin or TCPOBOP and not in those fed baicalein (inset). No such change in cyp2b10 mRNA content was observed in CAR KO mice.