Table 1.
NTF4 Sequence Variants Identified in 443 POAG Patients and 533 Controls
| Nucleotide Alteration | Amino Acid Change | POAG | Age at Onset (yrs) | Control | Age at Exam (yrs) | Reported Previously |
|---|---|---|---|---|---|---|
| c.263C > T | A88V | 1 | 73 | 5 | 67a | Yes |
| c.616C > T | R206W | 1 | 63 | 2 | 70a | Yes |
| c.86C > A | S29X | 0 | 1 | 56 | No | |
| c.266G > A | S89N | 1 | 62 | 1 | 56 | No |
| c.268C > T | R90C | 0 | 1 | 56 | No | |
| c.340C > G | R114G | 0 | 1 | 74 | No | |
| c.398G > A | R133H | 1 | 40 | 0 | No | |
| c.418C > T | R140C | 0 | 1 | 70 | No | |
| c.620C > T | T207I | 1 | 40 | 0 | No | |
| Total | 5 | 12 | ||||
a
Age at exam for these two variants is the mean age at exam.