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. 2010 Mar 12;86(3):378–388. doi: 10.1016/j.ajhg.2010.01.030

Figure 4.

Figure 4

Conserved Synteny of a Part of Human Chromosome 9q with Mouse Chromosome 2 and Expression Profile of TPRN in Several Tissues

(A) Part of human chromosome 9q, 17.71 Mb at the telomeric end, is syntenic to 14.62 Mb of mouse chromosome 2, which also includes 2.9 Mb of the DFNB79 linkage interval. Vertical lines (not drawn to scale) between the two chromosomal segments show the syntenic region, with five closely linked orthologous genes on each side of the DFNB79 gene. On the basis of conserved synteny and sequence comparison (see Figure 5), C430004E15Rik is the mouse ortholog of human TPRN.

(B) Arrows indicate the position of the forward and reverse primer used to amplify the C430004E15Rik transcript from mouse multiple-tissue cDNA libraries. Expected cDNA and gDNA product sizes are 2.4 kb and 6.9 kb, respectively. Amplimers were sequence confirmed.