TABLE 4.

Conditional logistic regression analysis for the risk of chronic atrophic gastritis using nonatrophic gastritis subjects as control

NAG*		ChAG†
Genotype	n (%)	n (%)	OR (95% CI)‡	P value‡
IL-1B-511
T/T	55 (64.0)	15 (34.9)	1.0 (Reference)
C/T	28 (32.6)	21 (48.8)	4.8 (1.65–13.83)	0.004
C/C	3 (3.5)	7 (16.3)	11.2 (2.27–55.37)	0.003
C carrier§	31 (36.0)	28 (65.1)	5.6 (2.02–15.51)	0.001
IL-1RN
L/L	30 (34.9)	13 (31.0)	1.0 (Reference)
*2/L	46 (53.5)	21 (50.0)	1.0 (0.44–2.34)	0.98
*2/*2	10 (11.6)	8 (19.0)	1.6 (0.48–5.39)	0.43
*2 carrier¶	56 (65.1)	29 (69.0)	1.1 (0.50–2.48)	0.79

Controls and cases are matched 2:1 for age, sex, and environmental factors.

^*Nonatrophic gastritis (controls).

^†Chronic atrophic gastritis (cases).

^‡Conditional logistic regression model adjusted for H. pylori infection.

^§Subjects with genotype C/T or C/C.

^¶Subjects with genotype *2/L or *2/*2.