TABLE 5.

Conditional logistic regression analysis for the risk of gastric cancer using nonatrophic gastritis subjects as control

NAG*		GC†
Genotype	n (%)	n (%)	OR (95% CI)‡	P value‡
IL-1B-511
T/T	81 (60.9)	56 (42.1)	1.0 (Reference)
C/T	45 (33.8)	62 (46.6)	2.17 (1.23–3.84)	0.007
C/C	7 (5.3)	15 (11.3)	4.15 (1.33–12.93)	0.014
C carrier§	52 (39.1)	77 (57.9)	2.36 (1.36–4.11)	0.002
IL-1RN
L/L	49 (36.8)	46 (34.6)	1.0 (Reference)
*2/L	68 (51.1)	71 (53.4)	1.03 (0.59–1.80)	0.91
*2/*2	16 (12.0)	16 (12.0)	0.86 (0.34–2.14)	0.75
*2 carrier¶	84 (63.2)	87 (65.4)	0.99 (0.57–1.71)	0.99

Controls and cases are matched 1:1 for age, sex, and environmental factors.

^*Nonatrophic gastritis (controls).

^†Gastric cancer (cases).

^‡Conditional logistic regression model adjusted for H. pylori infection.

^§Subjects with genotype C/T or C/C.

^¶Subjects with genotype *2/L or *2/*2.