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. Author manuscript; available in PMC: 2010 Apr 22.
Published in final edited form as: Neuroreport. 2009 Apr 22;20(6):606–610. doi: 10.1097/WNR.0b013e32832a0a98

Fig. 1.

Fig. 1

Time course for brain-derived neurotrophic factor (BDNF) protein expression in cortical tissue slices. Tissue slices were incubated with dopamine at various concentrations for 3, 12, or 24 h. The data represent the mean±SEM (n =9). Samples collated from three separate experiments and are presented as percentage change in BDNF protein expression compared with control samples. Basal levels of BDNF protein expression varied among the tested brain regions, with the hippocampus having the highest levels of the expressed protein. Slices prepared from the frontal cortex showed a significant increase in BDNF protein expression in response to 300 µM dopamine after 24 h incubation. ***P<0.001 compared with control as determined by one-way analysis of variance followed with Tukey’s post-hoc analysis.