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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Nat Neurosci. 2009 Nov 15;12(12):1534–1541. doi: 10.1038/nn.2446

Figure 4. Putative Draper and CED-1 homologs, Jedi-1 and MEGF10, are expressed in developing peripheral glial cells.

Figure 4

(a) Schematic representation of the modular architecture of Draper, CED-1 and possible mammalian homologs. A key for the predicted domains and motifs is shown on the bottom. Also see Supplementary Fig. 1 for the sequence alignments of their predicted intracellular domains. (b) RT-PCR detection of Jedi-1, Megf10, or Megf11 mRNA in E13 mouse brain, heart, spinal cord [SpC], whole DRG, and purified DRG neurons or satellite glial cells. 1 Kb DNA markers are on the left. (c) Jedi-1 and Megf10 transcripts were detected in mouse DRG and developing glial cells alongside axons. The developmental stages of the embryos are indicated on the left. Saggital sections; dorsal on the left. Arrowheads indicate the nerves.