Skip to main content
. Author manuscript; available in PMC: 2010 Mar 8.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2004 Oct;45(10):3733–3739. doi: 10.1167/iovs.04-0307

FIGURE 6.

FIGURE 6

Effect of bestrophin and bestrophin mutants on LP luminance response. RPE-generated ERG components were recorded in response to increasing luminance (color coded as indicated for A) in rats injected subretinally with 4.66 × 107 pfu of replication-defective adenovirus vectors with an empty expression cassette (control) or driving expression of bestrophin (WT) bestrophin-W93C (W93C) or bestrophin-R218C (R218C; see color codes beneath B and C). Mean isolated LPs collected between 110 and 300 seconds were normalized to the 110-second data point (A). (B) Mean LP amplitudes; (C) log τ. Data are the mean ± SE, with 4 ≤ n ≤ 12.