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Naka-Rushton Parameters’ for Eyes Overexpressing Bestrophin and Bestrophin Mutants
| Parameter | Control n = 11 |
WT n = 19 |
R218C n = 9 |
W93C n = 12 |
|---|---|---|---|---|
| Rmax (µV) | 0.69 ± 0.16 | 0.58 ± 0.20 | 0.78 ± 0.09 | 0.76 ± 0.28 |
| n | 1.12 ± 0.10 | 1.09 ± 0.23 | 1.02 ± 0.09 | 1.05 ± 0.17 |
| K (cd-sec/m2) | 1.99 ± 1.98 | 3.33 ± 5.49 | 2.27 ± 2.07 | 3.64 ± 2.84 |
Parameter values for transduced eyes expressed relative to the values obtained from the nonsurgical eye. Data are the mean ± SD.
