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. Author manuscript; available in PMC: 2010 Mar 8.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2008 Jun 6;17(6):1360–1367. doi: 10.1158/1055-9965.EPI-07-2878

Table 1.

Expected number of colorectal cancer cases depending on proliferation rate, mutation rate, and starting age of folic acid supplementation use.

Proliferation Increase (%) Mutation Reduction (%) Folic acid supplementation starting at age
2 20 40
Expected number of colorectal cancer cases per 100,000 individuals at risk
0 0 3319 3319 3319
Change in colorectal cancer cases
0 10 −687 −298 −193
0 20 −1274 −583 −397
10 0 +1286 +1223 +732
10 10 +353 +826 +511
10 20 −455 +449 +275
20 0 +2631 +2565 +1571
20 10 +1451 +2051 +1320
20 20 +419 +1570 +1053