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P2D5-treatment decreases myocardial neutrophil accumulation. LV neutrophil (PMN) accumulation was significantly increased in the untreated ZDF animals compared with non-diabetic and anti-complement treated animals. Treatment with anti-MBL (P2D5) effectively ameliorated the effect of diabetes on PMN accumulation since there is no difference between non-diabetic (ZLC) and ZDF+P2D5 LV PMN counts. *p<0.05 ZLC+PBS vs. ZDF+PBS; #p<0.05 ZDF+FUT and ZDF+P2D5 vs. ZDF+PBS.
