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. Author manuscript; available in PMC: 2010 Mar 8.
Published in final edited form as: Diab Vasc Dis Res. 2009;6(3):172–180. doi: 10.1177/1479164109336051

Figure 5.

Figure 5

P2D5-treatment decreases myocardial ICAM-1 expression. Treatment with the broad complement inhibitor FUT-175 (ZDF+FUT, grey bar) resulted in significantly decreased areas of vascular ICAM-1 expression compared to both untreated ZLC (ZLC+PBS, open bar) and untreated ZDF (ZDF+PBS, black bar) rats. Anti-MBL treatment (ZDF+P2D5, hashed bar) was effective at decreasing ICAM expression compared to ZLC+PBS and ZDF+PBS, however, there was more ICAM expression in P2D5-treated ZDF rats than in FUT-175 treated ZDF rats. *p<0.001 ZLC+PBS vs. ZDF+PBS; #p<0.001 ZDF+FUT and ZDF+P2D5 vs. ZDF+PBS; $p<0.001 ZDF+FUT vs. ZDF+P2D5.