Table 5. Predictors of subnormal weight (<–2 s.d.) at 20 months corrected age, results of stepwise logistic regression analysis.
| Variable | Stage I | Stage II | Stage II | Stage IV | ||||
|---|---|---|---|---|---|---|---|---|
| OR | (95% CI) | OR | (95% CI) | OR | (95% CI) | OR | (95% CI) | |
| Time period (I vs II) | 0.39 | (0.21,0.72)** | 0.34 | (0.17,0.71)** | 0.26 | (0.12,0.56)** | 0.26 | (0.12,0.58)** |
| Sociodemographic status | ||||||||
| Maternal education <high school | 0.86 | (0.38,1.96) | 0.81 | (0.35,1.88) | 0.96 | (0.41,2.26) | 0.97 | (0.40,2.31) |
| Race | 0.87 | (0.48,1.60) | 0.83 | (0.45,1.55) | 0.75 | (0.39,1.42) | 0.71 | (0.37,1.37) |
| Sex of child | 1.39 | (0.77,2.50) | 1.41 | (0.77,2.57) | 1.44 | (0.78,2.69) | 1.43 | (0.76,2.71) |
| Multiple birth | 1.21 | (0.56,2.62) | 1.17 | (0.52,2.63) | 1.42 | (0.61,3.30) | 1.32 | (0.56,3.12) |
| Neonatal therapy | ||||||||
| Surfactant | 1.97 | (0.59,6.64) | 2.02 | (0.58,7.12) | 2.40 | (0.65,8.83) | ||
| Postnatal steroids | 1.17 | (0.59,2.33) | 0.77 | (0.36,1.65) | 0.65 | (0.30,1.43) | ||
| Indomethacin | 1.95 | (0.95,3.98) | 1.94 | (0.93,4.05) | 1.85 | (0.88,3.90) | ||
| PDA ligation | 0.78 | (0.40,1.53) | 0.66 | (0.32,1.33) | 0.60 | (0.29,1.24) | ||
| Neonatal morbidity | ||||||||
| Severity of lung diseasea | 1.02 | (1.00,1.03)* | 1.01 | (1.00,1.03)* | ||||
| Severely abnormal ultrasoundb | 2.49 | (1.17,5.30)* | 1.56 | (0.68,3.61) | ||||
| Neurosensory outcome | 3.03 | (1.39,6.62)** | ||||||
Abbreviations: 95% C.I., 95% confidence interval; OR, odds ratio; PDA, patent ductus arteriosus.
a
Days on ventilator.
b
Includes grades III–IV hemorrhage, periventricular leukomalacia and ventricular dilatation at discharge.
*P<0.05, **P<0.001.