Table 2.
BCCA Population-Derived Cox Regression Hazard Ratios for the Revised IBTR! Version 2.0 Nomogram
| Characteristic | Hazard Ratio | 95% CIs |
|---|---|---|
| Age, years | ||
| ≤ 40 | 2.03 | 1.36 to 3.01 |
| 41-45 | 1.47 | 0.99 to 2.18 |
| 46-50 | 0.86 | 0.56 to 1.31 |
| 51-55 | 1.00 | |
| 56-60 | 0.71 | 0.45 to 1.13 |
| 61-65 | 0.74 | 0.47 to 1.15 |
| 66-70 | 0.74 | 0.47 to 1.14 |
| > 70 | 0.53 | 0.33 to 0.83 |
| LVI | ||
| Positive | 1.12 | 0.86 to 1.46 |
| Negative | 1.00 | |
| Unknown | 0.92 | 0.47 to 1.77 |
| Margin, mm | ||
| Positive | 2.19 | 1.65 to 2.91 |
| Close (< 2 mm) | 0.97 | 0.13 to 6.94 |
| Negative (> 2 mm) | 1.00 | |
| Unknown | 1.83 | 1.19 to 2.81 |
| Hormone therapy | ||
| Yes | 0.73 | 0.56 to 0.95 |
| No | 1.00 | |
| Chemotherapy | ||
| Yes | 0.79 | 0.59 to 1.07 |
| No | 1.00 | |
| Tumor grade | ||
| I | 0.70 | 0.48 to 1.01 |
| II | 1.00 | |
| III | 1.55 | 1.22 to 1.97 |
| Unknown | 1.20 | 0.69 to 2.08 |
| Tumor size, cm | ||
| ≤1 | 1.40 | 1.08 to 1.82 |
| 1.1-2 | 1.00 | |
| > 2 | 1.07 | 0.81 to 1.41 |
Abbreviations: BCCA, British Columbia Cancer Agency; IBTR, ipsilateral breast tumor recurrence; LVI, lymphovascular invasion.