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(A) Ad-LacZ was effective in infecting both granulosa (gr) cells and stromal (st) cells when delivered by direct intra-ovarian injection in nude mice (108 PFU/ovary), (o) indicates ooplasm; (B) Section of liver and (C) lung from nude mice treated by direct intraovarian injection with Ad-LacZ (103 PFU/ovary). They appear healthy with no LacZ (blue) expression. These photos were taken 4 weeks post-inoculation, H&E, ×400.
