Table 2.
UK ADC: demographics and clinical indices
| Diabetics | Non-diabetics | p-value | |
|---|---|---|---|
| Demographics | |||
| N | 50 | 89 | – |
| Age at death, yrs (mean±SD) | 84.7±8.0 | 88.2±6.7 | <0.011 |
| Sex (%F) | 54 | 63 | NS2 |
| Formal education, yrs (mean±SD) | 15.6±2.6 | 16.0±2.0 | NS1 |
| ApoE alleles (2/3/4), % | 4/84/12 | 11/76/13 | NS3 |
| Last MMSE score (mean±SD) | 26.4±5.1 | 24.4±7.4 | NS1 |
| Interval between last evaluation and death, yrs (mean±SD) | 0.64 | 0.96 | NS1 |
| Clinical parameters | |||
| Depression, % | 20 | 20 | NS2 |
| CABG, % | 14 | 7 | NS3 |
| Peripheral vascular disease, % | 26 | 15 | NS2 |
| TIA, % | 14 | 8 | NS2 |
| Hypertension, % | 64 | 55 | NS2 |
| Daily intake of drugs/meds (mean±SD) | 12.2±7.7 | 19.8±8.5 | <0.00011 |
The demographic and clinical characteristics between diabetics (N=50) and non-diabetics (N=89) in the BRAiNS program at the UK ADC. This group, which was recruited from non-demented individuals, has been described previously [245]. The demographic and clinical indices are similar between diabetics and non-diabetics. The clinical parameters were dichotomous (0 or 1) except for “Number of drugs” (range: 2–39). Definitions: ApoE = Apolipoprotein E; MMSE = Mini-mental status examination (0–30 scale); CABG = coronary artery bypass graft operation; TIA = history of transient ischemic attack(s).
Statistical tests:
1
Two-tailed Student’s t test
2
Chi-square
3
Fisher’s exact test.