Table 1.

Patient Demographic and Clinical Characteristics

Characteristic	HIF-1α Positive (n = 93)		HIF-1α Negative (n = 60)		P
	No.	%	No.	%
Age
Median	59		65		.163
Mean	59		62
Range	20-85		22-85
Stage
I-II	37	39	18	30	.218
III-IV	56	61	42	70
ECOG PS
0-1	58	62	40	67	.588
≥ 2	35	38	20	33
LDH
Normal	36	39	25	42	.715
Elevated	57	61	35	58
Extranodal sites
0-1	65	67	44	73	.646
≥ 2	28	33	16	27
IPI score
0-2	48	52	29	48	.692
3-5	45	48	31	52

Abbreviations: HIF, hypoxia-inducible factor; ECOG, Eastern Cooperative Oncology Group; PS, performance status; LDH, lactate dehydrogenase; IPI, International Prognostic Index.