Table 3.

Comparison of HIF-1α Protein Expression With Other Biomarkers in R-CHOP-Treated Patients (n = 78)

Biomarker	HIF-1α Expression		P†
	Positive	Negative
BCL2*
Positive	32	21	.54
Negative	16	8
CD10
Positive	18	12	.81
Negative	31	17
MUM-1*
Positive	34	16	.24
Negative	15	12
BCL6*
Positive	45	19	.004
Negative	3	10
FOXP1
Positive	14	10	.59
Negative	35	19

Abbreviations: HIF, hypoxia-inducible factor; R-CHOP, rituximab with cyclophosphamide, doxorubicin, oncovin, and prednisone.

^*One sample in each group could not be scored.

^†Two-sided P value.