Table 2.
Prognostic Factors With Associated 3-Year Survival Rates Using Univariate Analysis
Variable | No. of Patients | Survival |
|||||
---|---|---|---|---|---|---|---|
PFS |
OS |
||||||
3-Year Rate (%) | 95% CI | P | 3-Year Rate (%) | 95% CI | P | ||
Performance status | |||||||
0-1 | 55 | 67 | 52 to 78 | .0012 | 73 | 59 to 83 | .0003 |
2-4 | 25 | 36 | 18 to 54 | 35 | 15 to 56 | ||
Received first-line rituximab-based therapy | < .0001 | .0001 | |||||
No | 21 | 21 | 7 to 42 | 33 | 14 to 53 | ||
Yes | 59 | 70 | 57 to 81 | 73 | 58 to 83 | ||
Albumin | .03 | .005 | |||||
Normal | 56 | 76 | 52 to 90 | 86 | 62 to 95 | ||
Low | 23 | 50 | 36 to 62 | 53 | 38 to 65 | ||
CNS involvement | .02 | .03 | |||||
Absent | 70 | 61 | 48 to 72 | 65 | 52 to 76 | ||
Present | 10 | 30 | 7 to 58 | 40 | 12 to 67 | ||
Bone marrow involvement | .0007 | .0006 | |||||
Absent | 57 | 66 | 51 to 77 | 71 | 57 to 81 | ||
Present | 12 | 18 | 3 to 44 | 18 | 3 to 44 | ||
> 1 extranodal site | .06 | .03 | |||||
No | 50 | 64 | 48 to 76 | 72 | 57 to 82 | ||
Yes | 28 | 42 | 24 to 59 | 43 | 23 to 61 |
NOTE. The 3-year PFS and OS by Kaplan-Meier analysis are reported with their associated 95% CIs.
Abbreviations: PFS, progression-free survival; OS, overall survival.