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Natural killer (NK) cell engraftment and cytotoxicity. (A) Number of NK cells per microliter of blood. (B) Cytotoxicity against K562 cells with a target:effector cell ratio of 1:2. (C) Absolute number of killer immunoglobulin-like receptor (KIR)–mismatched NK cells. (D) Percentage of KIR-mismatched NK cells on days 2, 7, 14, 21, or 28. Gray areas in (A) and (B) represent the normal range established by analyzing donor blood before transplantation.
