Table 2.
Response
| Overall Radiologic Response* | Enzastaurin (n = 174) |
Lomustine (n = 92) |
Fisher's Exact P† | ||
|---|---|---|---|---|---|
| No. | % | No. | % | ||
| Objective response | 5 | 2.9 | 4 | 4.3 | .501 |
| Stable disease | 67 | 38.5 | 33 | 35.9 | .692 |
| Progressive disease | 72 | 41.4 | 38 | 41.3 | 1.000 |
| Unknown | 30 | 17.2 | 17 | 18.5 | .866 |
| Duration of response,‡ months | |||||
| Range | 4.14-9.63 | 2.79-9.62 | — | ||
*
Objective response was defined as decreased or no enhancement on the post-contrast T1 images and stability or improvement on fluid-attenuated inversion recovery/T2 images.
†
Comparison between regimens was based on unadjusted normal distribution approximation using the Fisher's exact test.
‡
Duration of response was measured from the date when the criteria were first met for response until the first date of progressive disease or death from any cause, whichever occurred first.