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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Brain Behav Immun. 2009 Dec 24;24(3):502–511. doi: 10.1016/j.bbi.2009.12.008

Fig. 2. Locomotor activity and body temperature response to LPS in mice sensitized to methamphetamine.

Fig. 2

Change in body weight (A) and Tb and locomotor activity in non-sensitized (B and C) and sensitized (D and E) mice after LPS and/or MA. Mice were subjected to a 5d regimen of 0 or 1mg/kg MA per day and then injected with LPS and/or MA 72h later (n=5-10 per group). Open circles represent saline administration, open triangles respresent MA administration, closed circles represent LPS administration and closed triangles represent mice co-administered MA and LPS. Arrow = injection, dark bar = lights off. For Tb there were significant main effects of Sensitization and LPS as well as a significant Sensitization × LPS interaction.