Table 2.
Ki (nM) |
Selectivity |
||||
---|---|---|---|---|---|
Compound | DAT | SERT | NET | SERT/DAT | NET/DAT |
29 | 1.70 | 85.5 | >10,000 | 50.3 | >5882 |
30 | 2.54 | 24.2 | >10,000 | 9.5 | >3937 |
31 | 0.24 | 0.85 | 91 | 3.5 | 379 |
32 | 0.17 | 0.21 | 57 | 1.2 | 335 |
Ki (nM) |
Selectivity |
||||
---|---|---|---|---|---|
Compound | DAT | SERT | NET | SERT/DAT | NET/DAT |
29 | 1.70 | 85.5 | >10,000 | 50.3 | >5882 |
30 | 2.54 | 24.2 | >10,000 | 9.5 | >3937 |
31 | 0.24 | 0.85 | 91 | 3.5 | 379 |
32 | 0.17 | 0.21 | 57 | 1.2 | 335 |