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. 2010 Feb;21(2):345–352. doi: 10.1681/ASN.2009060636

Table 4.

Adjusted all-cause mortality HRs associated with AKI for patients with renal recovery or without deterioration of kidney function

Baseline eGFR (ml/min per 1.73 m2) With AKI (n [%]) No AKI (n [%]) Adjusted Mortality HRa 95% CI
All 25,564 462,394 1.47 1.43 to 1.51
≥90 9983 (39.1) 176,409 (38.2) 1.52 1.46 to 1.59
≥60, <90 9630 (37.7) 217,931 (47.1) 1.39 1.33 to 1.45
≥45, <60 3915 (15.3) 50,694 (11.0) 1.39 1.31 to 1.48
≥30, <45 2036 (8.0) 17,360 (3.8) 1.21 1.12 to 1.30

A patient is considered to have recuperated or not had deterioration of kidney function when there is no decrease from the baseline eGFR to the eGFR after discharge > 10% of the baseline eGFR. When postdischarge creatinine was missing, postdischarge eGFR was calculated using imputed creatinine by multiple imputation; however, a baseline eGFR value was required to be included. A patient may have been included in the “no AKI” group because the ratio of the highest to lowest creatinine within the baseline period was <1.5 but still not included in this analysis when eGFR decrease was >10% when baseline and postdischarge eGFR values were compared.

aAdjusted for demographics, comorbidities and medication use, and hospitalization details. The reference is the “no AKI” group.