Figure 7.

T lymphocyte [cytotoxic]_Cancer cell (7A) and T lymphocyte [cytotoxic]_Vaccine cell (7B) as instances of the "Cell_Cell_Interaction" concept in models related to immunotherapy, as defined in CMM. These instance are shown as Tc CC and Tc VC in Fig. 2. The interaction between the T cell receptor (TR), on the surface of the T lymphocyte [cytotoxic], and the pMHC-I, on the surface of the cancer cell or vaccine cell, is also an instance of the "Molecule_Molecule_Interaction". It represents an additional example of interactions that bridges the gap between cell and molecule levels in the adaptive immune response (IMGT Education, http://www.imgt.org) [10].