Table 1.

Overall Reporting Quality items

Item	Description
1. Title or Abstract	The title or the abstract states the study is a randomized controlled trial.
2. Introduction	Appropriate description of the scientific background and explanation of the rationale.
Methods:
3. Participants	Eligibility criteria for participants are clearly described.
4. Interventions	Precise details of the interventions intended in each group are provided.
5. Outcomes	Clear definition of primary and secondary outcome measures is provided.
6. Objectives	Specific objectives or research question or hypotheses are stated.
7. Sample size	Clear description on how the sample size was determined is given.
8. Randomization sequence generation	The method used to generate the random allocation sequence is stated.
9. Randomization implementation	The separation of generator of the allocation sequence and executor is described.
10. Statistical methods	Statistical methods used to compare groups for primary outcomes, subgroup analyses or adjusted analyses were properly described.
Results:
11. Participants flow	Number of participants randomly assigned, receiving intended treatment, completing the study protocol, and analyzed for primary outcome are given.
12. Recruitment	Dates defining the periods of recruitment and follow-up are provided.
13. Baseline data	Baseline demographic and clinical characteristics of each group are properly described.
14. Outcomes and estimation	For each primary and secondary outcome, a summary of results for each group and the estimated effect size and its precision (e.g., 95% CI) is provided.
15. Adverse events	All important adverse events or side effects in each intervention group are described.

* Item 6 (Objectives) was excluded from OQS.