Figure 3.

Location of CUP and C/EBP binding sites in the 5′ flanking and 5′-UTRs of the C/EBPα gene. The transcriptional start site is indicated by a bent arrow and the translational start site by an ATG in the upper left of the boxed intronless coding region of the gene. The numbers refer to the number of nucleotides 5′ and 3′ (− and +, respectively) from the transcriptional start site. The open boxes in the 5′ flanking region and 5′-UTR represent CUP binding sites and the darkened box represents the C/EBP binding site. BamHI, SmaI, NruI, and NcoI indicate restriction enzyme cleavage sites.