Table 4.

Predictors of delay in parasite clearance on day 1 after treatment in children with acute falciparum malaria

Variables	Number enrolled	PC >2 d	Crude OR (95% CI)	P Value	Adjusted OR (95% CI)	P Value
Axillary temperature (°C)
<38.0	2326	1012	1		1
≥ 38.0	228	139	2.02 (1.53 -2.67)	<0.0001	1.80 (1.30-2.50)	< 0.001
Parasitaemia (/μl blood)
≤ 20,000	1328	463	1		1
>20,000	683	467	5.25 (4.20 - 6.48)	<0.0001	5.13 (4.14 - 6.35)	< 0.001
Drug treatment *
CQ	388	275	1	1	1
AQ	573	298	0.44 (0.33 - 0.58)	<0.0001	0.79 (0.63 - 0.98)	< 0.03
AQAS	142	14	0.05 (0.03 - 0.08)	<0.0001	0.24 (0.10 - 0.57)	< 0.0001
AQPS	69	26	0.24 (0.14 - 0.42)	<0.0001	0.44 (0.26 - 0.73)	0.002
AQSP	91	34	0.25 (0.15 - 0.39)	<0.0001	0.43 (0.29 - 0.68)	< 0.0001
AMQ	174	10	0.03 (0.01 - 0.05)	<0.0001	0.04 (0.02 - 0.09)	< 0.0001
AL	90	6	0.03 (0.01 - 0.07)	<0.0001	0.05 (0.02 - 0.12)	< 0.0001
AS	120	3	0.01 (0.00 - 0.03)	<0.0001	0.02 (0.00 - 0.06)	< 0.0001
COT	104	61	0.58 (0.37 - 0.91)	0.017	1.03 (0.68 - 1.36)	0.877
CQCP	315	189	0.61 (0.45 - 0.84)	0.002	1.09 (0.83 - 1.42)	0.512
CQKET	70	36	0.43 (0.25 - 0.73)	0.001	0.77 (0.47 - 1.25)	0.029
CQPS	107	46	0.31 (0.19 - 0.48)	<0.0001	0.54 (0.36 - 0.82)	0.004
MQ	176	40	0.12 (0.08 - 0.18)	<0.0001	0.21 (0.15 - 0.31)	< 0.0001
SP	291	186	0.72 (0.52 - 1.00)	0.055	-	-
SPP	42	13	0.18 (0.09 - 0.37)	<0.0001	0.33 (0.17 -0.98)	0.001

CI, confidence interval; OR, odd ratio; PC, parasite clearance

* Values of OR represent chances of delay in parasite clearance