Table 3.
Effects of Intervention on Antibiotic Use After the Index Consultation (by CRP Category) and Within a 28-Day Follow-Up. Exploratory Data on Antibiotic Use Per Respiratory Tract Infection
| Antibiotic Use | CRP Assistance % (n) | Control % (n) | RRa | 95% CI |
|---|---|---|---|---|
| After index consultation | 43.4 (56/129) | 56.6 (73/129) | 0.77 | 0.56–0.98 |
| Rhinosinusitis | 45.2 (33/73) | 60.3 (47/78) | ||
| LRTI | 41.1 (23/56) | 51.0 (26/51) | ||
| Within 28-day follow-up | 52.7 (68/129) | 65.1 (84/129) | 0.81 | 0.62–0.99 |
| Rhinosinusitis | 57.5 (42/73) | 69.2 (54/78) | ||
| LRTI | 46.4 (26/56) | 58.8 (30/51) | ||
| By CRP category | ||||
| 0–20 mg/L (n = 140) | 26.0 (19/73) | 49.3 (33/67) | ||
| 21–50 mg/L (n = 62) | 56.5 (13/23) | 59.0 (23/39) | ||
| 51–100 mg/L (n = 37) | 68.2 (15/22) | 66.7 (10/15) | ||
| >100 mg/L (n = 19) | 81.8 (9/11) | 87.5 (7/8) |
CI=confidence interval; CRP = C-reactive protein; LRTI = lower respiratory tract infection; RR = relative risk.
Note: Statistical testing was not performed on the exploratory data on antibiotic use per respiratory tract infections, as this trial was designed to detect differences between the total group of patients per group.
a Relative risks corrected for clustering.