Figure 5. Protein sequence alignment of Bma-RXR with RXRs and USPs.

RXR and USP sequences are shown above and below the filarial sequences respectively. Residues that are identical in a majority of the USP/RXRs shown are shaded in black. Residues that are biochemically similar are shadowed in gray. Functional regions (DBD, T/A Box and LBD helices) are underlined and amino acid residue numbers are indicated. Bma-RXR residues shared with all RXRs or USPs, and the AF2 are boxed. PCR primers used in cloning and mentioned in the text are indicated using the same labeling convention as in Fig. 1B.