Table 2.
Clinical features and susceptibility factors in 135 patients with PCT as related to HCV infection as the target variable.
| Clinical features and susceptibility factors |
Total studied |
Affected | HCV positive |
HCV negative |
p |
|---|---|---|---|---|---|
| (n) | (percent of those affected) | ||||
| Sex (M) | 135 | 93 | 80.7 | 19.3 | 0.0001 |
| Alcohol use | 128 | 112 | 75.0 | 25.0 | <0.0001 |
| Smoking | 118 | 96 | 80.2 | 19.8 | <0.0001 |
| HIV infection | 95 | 12 | 33.3 | 66.7 | 0.017 |
| Estrogen use | 45 | 29 | 41.4 | 58.6 | 0.75 |
| HFE mutations | 89 | 50 | 68.0 | 32.0 | 0.82 |
| Low erythrocyte UROD | 105 | 18 | 61.1 | 39.9 | 0.58 |
| Diabetes mellitus | 104 | 8 | 75 | 25 | 0.99 |
| Obesity (BMI ≥25) | 81 | 39 | 66.7 | 33.3 | 0.63 |
| Steatosis (liver biopsy) | 19 | 6 | 83 | 17 | 0.31 |