. Author manuscript; available in PMC: 2011 Apr 1.

Published in final edited form as: Acad Radiol. 2010 Jan 12;17(4):489–495. doi: 10.1016/j.acra.2009.11.004

Table 2.

CT measurements and correlations with lung function

	CT measurements		Correlations with pulmonary function tests

	Mean ± SD	(Range)	FEV₁%P	FEV₁/FVC	RV/TLC	DLco%P
Insp-LAA% (%)	14.1 ± 11.9	(1.2 – 49.7)	−0.625^a	−0.713^a	0.532^b	−0.606^a
Exp-LAA% (%)	9.3 ± 11.2	(0.6 – 46.8)	−0.637^a	−0.729^a	0.574^a	−0.633^a
Insp-MLD (HU)	−848.8 ± 35.7	(−906.3 – −755.3)	0.494^b	0.562^a	−0.397^c	0.284
Exp-MLD (HU)	−796.1 ± 60.7	(−893.4 – −660.5)	0.661^a	0.743^a	−0.607^a	0.411^c
MLD E/I ratio	0.94 ± 0.05	(0.78 – 0.99)	−0.583^a	−0.648^a	0.537^b	0.366^d
Insp-LV (L)	5.12 ± 1.27	(3.08 – 9.09)	−0.010	−0.198	−0.168	0.149
Exp-LV (L)	3.74 ± 1.07	(1.76 – 6.31)	−0.406^c	−0.588^a	0.252	−0.160
LV E/I ratio	0.73 ± 0.14	(0.39 – 0.95)	−0.563^a	−0.594^a	0.571^a	−0.358^d

p<0.0001;

p<0.001;

p<0.01;

p<0.05

Definition of abbreviations: insp = inspiratory, exp = expiratory, LAA% = low attenuation area percent (<−950HU), MLD = mean lung density, E/I = expiratory/inspiratory, LV = lung volume