Fig. 4.
Iodide and thyroglobulin (Tg) suppression of the expression of NIS and VEGF. Iodide suppressed the expression of NIS and VEGF at the mRNA level. A representative image of a Northern blot is shown in (A). The results of densitometric measurements are expressed relative to control in (B). (C) NIS and VEGF mRNA expression was restored by the removal of iodide from the medium. (D) Iodide and Tg synergistically suppressed the expression of NIS and VEGF. The results of densitometric measurements of different experiments are expressed as mean ± SD relative to control. Significant decreases are noted: ** p < 0.01.