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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: J Vasc Surg. 2009 Oct 17;51(3):736–746. doi: 10.1016/j.jvs.2009.07.102

Figure 5.

Figure 5

Flow mediated vasodilation in mature human saphenous vein grafts demonstrates a functional endothelium. Application of an occlusive blood pressure cuff (220 mmHg) to the proximal calf of a cohort of patients undergoing femoro-popliteal bypass grafts for 5 minutes produces an increase in blood flow and shear stress within the graft, A. In this cohort, flow mediated, endothelium dependent vasodilation was 5.3% and nitroglycerin mediated, endothelium independent (0.4 mg sublingual nitroglycerin) dilation was 3.7%.