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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Mutat Res. 2010 Jan 8;686(1-2):1–8. doi: 10.1016/j.mrfmmm.2009.11.012

Figure 4. FISH analysis for the X and Y chromosomes.

Figure 4

Analyses were performed on spontaneously arising GPI-negative sub-populations of Jurkat, HBL2, and PR1-C, isolated by sorting and proaerolysin selection. X and Y chromosome centromeric probes generate green and orange fluorescence respectively. Representative interphase and metaphase cells are shown. Spontaneous loss of the Y chromosome was observed, but not the spontaneous loss of the X chromosome in any of the cells analysed by FISH or G-banded karyotyping.