Fig. 4.
TG and HDL in Tshr- and Vil1-deficient mice. Means and SEM are given for each group maintained on a chow diet. A: Tshrhyt/hyt lipid testing. *There is no sex difference in T4 and TG between homozygous mutants versus wild-type (P = 0.4), thus data are presented sex-averaged. HDL is presented separately for each sex, because there was a significant difference between sexes (P < 0.01). B: Vil1−/− lipid testing. TG and HDL both had significant sex effects and thus are presented separately. TG (mg/dl), female Vil1−/− = 78 ± 7, Vil1+/+ = 97 ± 8 (P < 0.05); male Vil1−/− = 61 ± 9, Vil1+/+ = 80 ± 8 (P < 0.05); HDL (mg/dl), female Vil1−/− = 58 ± 2, Vil1+/+ = 45 ± 3 (P < 0.05); male, Vil1−/− = 70 ± 3, Vil1+/+ =65 ± 3 (P < 0.05). Male HDL values do not appear significant; however, in the context of a mixed model with sex as a fixed effect, TG and HDL are significantly different; P = 0.03, 0.006 for TG and HDL, respectively. N = 5 for each group.