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. 2008 Dec 23;17(3):516–523. doi: 10.1038/mt.2008.283

Figure 4.

Figure 4

Detection of adeno-associated viral (AAV) particles in the treated retina of D2. (a–c) Ultrathin sections of the portion of the retina representing the INL. (a) Portion of the retina where viral particles are found (indicated by a square). Bar = 20 µm. (b) Magnification of the area indicated in a. Vector particles are found inside of cellular structures (arrow). Bar = 1 µm. (c) Magnification of b to identify the hexagonal structure and the size of the particles of 21 nm. Bar = 100 nm. (d–f) Ultrathin sections of the portion of the retina representing the OPL. (d) Portion of the retina where viral particles are found (indicated by a square). Bar = 20 µm. (e) Magnification of the area indicated in d. Vector particles are found inside closed compartments (square). Bar = 1 µm. (f) Magnification of e. Bar = 200 nm. INL, inner nuclear layer; IPL, inner plexiform layer; OPL, outer plexiform layer.