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Severity and frequency of CIA in lentivirus-treated mice. (a) The severity and (b) frequency of arthritis in mice injected with LNT-GFP, LNT-Ii-CLIP, and LNT-Ii-CII viral particles 28 days before CII immunization. Data in a are presented as mean score ± SEM. *P < 0.05 LNT-Ii-CII versus LNT-Ii-CLIP; †P < 0.05 LNT-Ii-CII versus LNT-GFP; ‡P < 0.05 LNT-Ii-CLIP versus LNT-GFP.
